Kumar, Pradeep and Dubey, Abhishek and Harbindu, Anand (2012) Enantio- and diastereocontrolled conversion of chiral epoxides to trans-cyclopropane carboxylates: application to the synthesis of cascarillic acid, grenadamide and L-(−)-CCG-II. Organic and Biomolecular Chemistry, 10. pp. 6987-6994. ISSN 1477-0539

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Abstract

An efficient high yielding improved method for the enantio- and stereoselective cyclopropanation of chiral epoxides using triethylphosphonoacetate and base (Wadsworth-Emmons cyclopropanation) is reported. The utility of this protocol is illustrated by concise and practical synthesis of cascarillic acid, grenadamide and L-(-)-CCG-II, a cyclopropane containing natural products.

Item Type: Article
Subjects: Organic Chemistry
Divisions: UNSPECIFIED
Depositing User: Mr. Anand Harbindu
Date Deposited: 17 Jul 2012 05:10
Last Modified: 03 Mar 2015 09:31
URI: http://ncl.csircentral.net/id/eprint/1047

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